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geomx spatial transcriptomics platform  (Spatial Transcriptomics Inc)

 
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    Spatial Transcriptomics Inc geomx spatial transcriptomics platform
    Geomx Spatial Transcriptomics Platform, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/geomx+spatial+transcriptomics+platform/geomx/pm40578769-345-13-14
    Average 90 stars, based on 1 article reviews
    geomx spatial transcriptomics platform - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    In Situ:

    Article Title: Method for high‐plex analysis of immune cells in human skin using the GeoMx system
    Article Snippet: .. Several novel methods for in situ gene and protein expression have recently revolutionized the field of spatial visualization.13 Here, we demonstrate a method of pooling individually annotated skin cells and cell colocalizations using the GeoMX spatial transcriptomics platform to overcome the systems requirement for minimum sampling material. ..

    Expressing:

    Article Title: Method for high‐plex analysis of immune cells in human skin using the GeoMx system
    Article Snippet: .. Several novel methods for in situ gene and protein expression have recently revolutionized the field of spatial visualization.13 Here, we demonstrate a method of pooling individually annotated skin cells and cell colocalizations using the GeoMX spatial transcriptomics platform to overcome the systems requirement for minimum sampling material. ..

    Sampling:

    Article Title: Method for high‐plex analysis of immune cells in human skin using the GeoMx system
    Article Snippet: .. Several novel methods for in situ gene and protein expression have recently revolutionized the field of spatial visualization.13 Here, we demonstrate a method of pooling individually annotated skin cells and cell colocalizations using the GeoMX spatial transcriptomics platform to overcome the systems requirement for minimum sampling material. ..

    other:

    Article Title: Nurturing protectors: Macrophages in the human pancreatic islet.
    Article Snippet: The pancreas is a heterocrine gland, responsible for the exocrine secretion of digestive enzymes in the duodenum and the endocrine secretion of various essential blood glucose-regulating hormones.. The exocrine compartment of the pancreas comprises most of the tissue (>95%), whereas endocrine cells are scattered throughout and around the remaining tissue, arranged in distinctive structures known as the islets of Langerhans.. These islets constantly monitor and adjust blood glucose levels via the production of glucagon from a cells, insulin from b cells, and, to a lesser extent, somatostatin from d cells.

    Spatial Transcriptomics:

    Article Title: Interneuron transcriptomics reveals pathologic markers of Alzheimer's disease progression.
    Article Snippet: .. Fig. 1 Spatial transcriptomics of mouse brain and study scheme. (A) Schematic of GeoMx spatial transcriptomics platform for isolating Pv+, Sst+, and VGluT+ regions of interest (ROIs). ..



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    Representative H&E images of granulomas from A) Case 3, B) Case 2, and C) Case 4 showing a range of granuloma morphology with D) necrotizing granulomas, E) cellular non-necrotizing granulomas, and F) small, lymphocyte rich granulomas as assessed by a pulmonary pathologist using traditional morphological annotation. Regions of interest (ROIs) ( G-K ) were selected based on morphological and fluorescence staining for DNA (blue), CD3 (green), CD68/CD163 (red), and vimentin (yellow). ROIs bordering necrotic (G) granulomas and (H) solid or cellular granulomas were selected in addition to tertiary lymphoid structures (I), lymph node (J), and uninvolved lung (K) for spatial transcriptional profiling using the human whole <t>transcriptome</t> probe set using GeoMx (Bruker).
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    Image Search Results


    Representative H&E images of granulomas from A) Case 3, B) Case 2, and C) Case 4 showing a range of granuloma morphology with D) necrotizing granulomas, E) cellular non-necrotizing granulomas, and F) small, lymphocyte rich granulomas as assessed by a pulmonary pathologist using traditional morphological annotation. Regions of interest (ROIs) ( G-K ) were selected based on morphological and fluorescence staining for DNA (blue), CD3 (green), CD68/CD163 (red), and vimentin (yellow). ROIs bordering necrotic (G) granulomas and (H) solid or cellular granulomas were selected in addition to tertiary lymphoid structures (I), lymph node (J), and uninvolved lung (K) for spatial transcriptional profiling using the human whole transcriptome probe set using GeoMx (Bruker).

    Journal: bioRxiv

    Article Title: Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas

    doi: 10.1101/2025.03.10.642376

    Figure Lengend Snippet: Representative H&E images of granulomas from A) Case 3, B) Case 2, and C) Case 4 showing a range of granuloma morphology with D) necrotizing granulomas, E) cellular non-necrotizing granulomas, and F) small, lymphocyte rich granulomas as assessed by a pulmonary pathologist using traditional morphological annotation. Regions of interest (ROIs) ( G-K ) were selected based on morphological and fluorescence staining for DNA (blue), CD3 (green), CD68/CD163 (red), and vimentin (yellow). ROIs bordering necrotic (G) granulomas and (H) solid or cellular granulomas were selected in addition to tertiary lymphoid structures (I), lymph node (J), and uninvolved lung (K) for spatial transcriptional profiling using the human whole transcriptome probe set using GeoMx (Bruker).

    Article Snippet: Due to the limited data on the functional role and significance of MDSCs in TB infected lung tissues, we used an unbiased spatial whole transcriptome analysis (WTA) platform (GeoMx, Bruker, Inc) integrated with single-cell immunophenotyping via highly multiplexed tissue cyclic immunofluorescence (CyCIF) to initiate this study of human TB.

    Techniques: Fluorescence, Staining